Open access chemical and clinical probes to support drug discovery

被引：79

作者：

Edwards, Aled M. ^{[1
]}

Bountra, Chas ^{[2
]}

Kerr, David J. ^{[3
]}

Willson, Timothy M. ^{[4
]}

机构：

[1] Univ Toronto, Struct Genom Consortium, Toronto, ON, Canada

[2] Univ Oxford, Struct Genom Consortium, Oxford, England

[3] Qatar Fdn, Sidra Med & Res Ctr, Doha, Qatar

[4] GlaxoSmithKline, Discovery Med Chem, Res Triangle Pk, NC USA

来源：

NATURE CHEMICAL BIOLOGY | 2009年 / 5卷 / 07期

基金：

加拿大健康研究院; 英国惠康基金;

关键词：

ORPHAN NUCLEAR RECEPTORS; SUBSTANCE-P; SYNOVIAL-FLUID; PAIN; BRADYKININ; INHIBITORS; ARTHRITIS; GENOMICS;

D O I：

10.1038/nchembio0709-436

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Drug discovery resources in academia and industry are not used efficiently, to the detriment of industry and society. Duplication could be reduced, and productivity could be increased, by performing basic biology and clinical proofs of concept within open access industry-academia partnerships. Chemical biologists could play a central role in this effort.

引用

页码：436 / 440

页数：5

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