Architecture and function in the muscle sarcomere

被引：161

作者：

Squire, JM

机构：

[1] Biophysics Section, Blackett Laboratory, Imperial College

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 02期

关键词：

D O I：

10.1016/S0959-440X(97)80033-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Striated muscle sarcomeres in vertebrates comprise ordered arrays of actin and myosin filaments, organized by an elaborate protein scaffold. Recent innovative work in a number of laboratories has greatly improved our knowledge of these structures, their organization and their interactions. Structural details have been reported on myosin filaments, actin filaments, Z-bands, M-bands, titin, and nebulin. Time-resolved X-ray diffraction and electron microscopy are revealing the molecular movements involved in force production and regulation.

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页码：247 / 257

页数：11

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