Anaphylaxis: A review of causes and mechanisms

被引：308

作者：

Kemp, SF

Lockey, RF

机构：

[1] Univ S Florida, Coll Med, VA Med Ctr, Dept Internal Med,Div Allergy & Immunol, Tampa, FL 33612 USA

[2] Univ Mississippi, Med Ctr, Dept Med, Div Allergy & Immunol, Jackson, MS 39216 USA

[3] James A Haley Vet Hosp, Tampa, FL 33612 USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2002年 / 110卷 / 03期

关键词：

anaphylaxis; anaphylactoid reactions; immunopathologic mechanisms; pathophysiology; epinephrine;

D O I：

10.1067/mai.2002.126811

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Anaphylaxis is a life-threatening syndrome resulting from the sudden release of mast cell- and basophil-derived mediators into the circulation. Foods and medications cause most anaphylaxis for which a cause can be identified, but virtually any agent capable of directly or indirectly activating mast cells or basophils can cause this syndrome. This review discusses the pathophysiologic mechanisms of anaphylaxis, its causes, and its treatment.

引用

页码：341 / 348

页数：8

共 78 条

[1] TRIGGERING OF PLAQUE DISRUPTION AND ARTERIAL THROMBOSIS IN AN ATHEROSCLEROTIC RABBIT MODEL [J].