Epigenetic asymmetry of imprinted genes in plant gametes

被引:124
作者
Gutierrez-Marcos, Jose F.
Costa, Liliana M.
Dal Pra, Mauro
Scholten, Stefan
Kranz, Erhard
Perez, Pascual
Dickinson, Hugh G.
机构
[1] Univ Oxford, Dept Plant Sci, Oxford OX1 3RB, England
[2] Univ Hamburg, Biozentrum Klein Flottbek, D-22609 Hamburg, Germany
[3] Univ Hamburg, Bot Garten, D-22609 Hamburg, Germany
[4] Biogemma, F-63170 Clermont Ferrand, France
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1038/ng1828
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Plant imprinted genes show parent-of-origin expression in seed endosperm, but little is known about the nature of parental imprints in gametes before fertilization. We show here that single differentially methylated regions (DMRs) correlate with allele-specific expression of two maternally expressed genes in the seed and that one DMR is differentially methylated between gametes. Thus, plants seem to have developed similar strategies as mammals to epigenetically mark imprinted genes.
引用
收藏
页码:876 / 878
页数:3
相关论文
共 15 条
[1]   Dynamic regulatory interactions of Polycomb group genes:: MEDEA autoregulation is required for imprinted gene expression in Arabidopsis [J].
Baroux, U ;
Gagliardini, V ;
Page, DR ;
Grossniklaus, U .
GENES & DEVELOPMENT, 2006, 20 (09) :1081-1086
[2]   Gardening the genome:: DNA methylation in Arabidopsis thaliana [J].
Chan, SWL ;
Henderson, IR ;
Jacobsen, SE .
NATURE REVIEWS GENETICS, 2005, 6 (05) :351-360
[3]   DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in Arabidopsis [J].
Choi, YH ;
Gehring, M ;
Johnson, L ;
Hannon, M ;
Harada, JJ ;
Goldberg, RB ;
Jacobsen, SE ;
Fischer, RL .
CELL, 2002, 110 (01) :33-42
[4]   Duplicated fie genes in maize:: Expression pattern and imprinting suggest distinct functions [J].
Danilevskaya, ON ;
Hermon, P ;
Hantke, S ;
Muszynski, MG ;
Kollipara, K ;
Ananiev, EV .
PLANT CELL, 2003, 15 (02) :425-438
[5]   DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation [J].
Gehring, M ;
Huh, JH ;
Hsieh, TF ;
Penterman, J ;
Choi, Y ;
Harada, JJ ;
Goldberg, RB ;
Fischer, RL .
CELL, 2006, 124 (03) :495-506
[6]   Imprinting in the endosperm: a possible role in preventing wide hybridization [J].
Gutierrez-Marcos, JF ;
Pennington, PD ;
Costa, LM ;
Dickinson, HG .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 2003, 358 (1434) :1105-1111
[7]   Polycomb group complexes self-regulate imprinting of the polycomb group gene MEDEA in Arabidopsis [J].
Jullien, PE ;
Katz, A ;
Oliva, M ;
Ohad, N ;
Berger, F .
CURRENT BIOLOGY, 2006, 16 (05) :486-492
[8]  
JULLIEN PE, 2006, PLANT CELL
[9]   One-way control of FWA imprinting in Arabidopsis endosperm by DNA methylation [J].
Kinoshita, T ;
Miura, A ;
Choi, YH ;
Kinoshita, Y ;
Cao, XF ;
Jacobsen, SE ;
Fischer, RL ;
Kakutani, T .
SCIENCE, 2004, 303 (5657) :521-523
[10]   The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprinting [J].
Köhler, C ;
Page, DR ;
Gagliardini, V ;
Grossniklaus, U .
NATURE GENETICS, 2005, 37 (01) :28-30