Chemiluminescence of beta-lactam antibiotics following oxidation by potassium superoxide

被引：16

作者：

Sun, JS ^{[1
]}

Schulman, SG ^{[1
]}

Perrin, JH ^{[1
]}

机构：

[1] UNIV FLORIDA,COLL PHARM,GAINESVILLE,FL 32610

来源：

ANALYTICA CHIMICA ACTA | 1997年 / 338卷 / 1-2期

关键词：

chemiluminescence; potassium superoxide; 18-crown-6-ether; acetonitrile; beta-lactam antibiotics;

D O I：

10.1016/S0003-2670(96)00450-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The complexes formed by potassium superoxide (KO2) with 18-crown-6-ether in acetonitrile are stable and extremely strong oxidizers. Eleven different beta-lactam antibiotics were tested for chemiluminescence (CL) by using such an oxidizer and seven of them gave measurable signals. A linear relationship was obtained between the chemiluminescent peak height and the concentration of penicillin G and dicloxacillin.

引用

页码：1 / 2

页数：2

共 5 条

[1] INACTIVATION OF PENICILLIN-G BY ACIDS - A REACTION-KINETIC INVESTIGATION [J].