General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis

被引：22

作者：

Baxter, NJ ^{[1
]}

Laws, AP ^{[1
]}

Rigoreau, LJH ^{[1
]}

Page, MI ^{[1
]}

机构：

[1] Univ Huddersfield, Dept Chem & Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 23期

关键词：

D O I：

10.1039/a907501a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The hydrolysis of the four-membered ring sulfonamide N-benzyl beta-sultam is catalysed by carboxylic acids, which is attributed to specific acid-nucleophilic catalysis with the intermediate formation of a mixed anhydride which can be trapped with aniline.

引用

页码：2401 / 2402

页数：2

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