Microbiologic Methods Utilized in the MAL-ED Cohort Study

被引：80

作者：

Houpt, Eric ^{[1
]}

Gratz, Jean ^{[1
]}

Kosek, Margaret ^{[2
]}

Zaidi, Anita K. M. ^{[3
]}

Qureshi, Shahida ^{[3
]}

Kang, Gagandeep ^{[4
]}

Babji, Sudhir ^{[4
]}

Mason, Carl ^{[5
]}

Bodhidatta, Ladaporn ^{[5
]}

Samie, Amidou ^{[6
]}

Bessong, Pascal ^{[6
]}

Barrett, Leah ^{[1
]}

Lima, Aldo ^{[7
]}

Havt, Alexandre ^{[7
]}

Haque, Rashidul ^{[8
]}

Mondal, Dinesh ^{[8
]}

Taniuchi, Mami ^{[1
]}

Stroup, Suzanne ^{[1
]}

McGrath, Monica ^{[9
]}

Lang, Dennis ^{[9
,10
]}

机构：

[1] Univ Virginia, Charlottesville, VA 22908 USA

[2] Johns Hopkins Univ, Baltimore, MD USA

[3] Aga Khan Univ, Naushahro Feroze, Pakistan

[4] Christian Med Coll & Hosp, Vellore, Tamil Nadu, India

[5] Armed Forces Res Inst Med Sci, Bangkok 10400, Thailand

[6] Univ Venda, Thohoyandou, South Africa

[7] Univ Fed Ceara, Fortaleza, Ceara, Brazil

[8] Icddr B, Dhaka, Bangladesh

[9] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA

[10] Fdn Natl Inst Hlth, Bethesda, MD USA

来源：

CLINICAL INFECTIOUS DISEASES | 2014年 / 59卷

基金：

美国国家卫生研究院; 比尔及梅琳达.盖茨基金会;

关键词：

culture; ELISA; enteropathogen; microscopy; PCR; DIARRHEAGENIC ESCHERICHIA-COLI; HELICOBACTER-PYLORI INFECTION; DEVELOPING-COUNTRIES; INTESTINAL PERMEABILITY; YOUNG-CHILDREN; ENZYME-IMMUNOASSAY; HELMINTH INFECTION; COGNITIVE FUNCTION; GROWTH IMPAIRMENT; PERUVIAN CHILDREN;

D O I：

10.1093/cid/ciu413

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A central hypothesis of The Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study is that enteropathogens contribute to growth faltering. To examine this question, the MAL-ED network of investigators set out to achieve 3 goals: (1) develop harmonized protocols to test for a diverse range of enteropathogens, (2) provide quality-assured and comparable results from 8 global sites, and (3) achieve maximum laboratory throughput and minimum cost. This paper describes the rationale for the microbiologic assays chosen and methodologies used to accomplish the 3 goals.

引用

页码：S225 / S232

页数：8

共 42 条

[31] Diagnosing norovirus-associated infectious intestinal disease using viral load [J].