Serologic and molecular detection of Ehrlichia chaffeensis and Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in Korean patients

被引：70

作者：

Heo, EJ

Park, JH

Koo, JR

Park, MS

Park, MY

Dumler, JS

Chae, JS ^{[1
]}

机构：

[1] Chonbuk Natl Univ, Coll Vet Med, Dept Vet Internal Med & Clin Pathol, Jeonju 561756, Jeonbuk, South Korea

[2] Scientec Lab Ctr Co Ltd, Mol BioNet Res Inst, Taejon 306030, South Korea

[3] Natl Inst Hlth, Dept Microbiol, Div Rickettsial & Zoonot Dis, Seoul 122701, South Korea

[4] Johns Hopkins Med Inst, Dept Pathol, Div Med Microbiol, Baltimore, MD 21287 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 08期

关键词：

D O I：

10.1128/JCM.40.8.3082-3085.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Sera from 491 Korean patients with acute febrile diseases were tested for Ehrlichia chaffeensis and Anaplasma phagocytophila antibodies by indirect immunofluorescence assay (IFA), Western blotting, and TaqMan realtime PCR. Overall, 0.4% of sera reacted with E. chaffeensis, and 1.8% reacted with A. phagocytophila in IFAs. This is the first report of detection of antibodies to A. phagocytophila and E. chaffeensis in Korea and suggests the presence of A. phagocytophila and E. chaffeensis or antigenically similar species.

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页码：3082 / 3085

页数：4

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