Monocyte chemoattractant protein-1 (MCP1) promoter-2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population

被引：35

作者：

Pae, CU

Yu, HS

Kim, TS

Lee, CU

Lee, SJ

Jun, TY

Lee, C

Serretti, A

Paik, IH

机构：

[1] Catholic Univ Korea, Coll Med, Dept Psychiat, Kangnam St Marys Hosp, Seoul 137701, South Korea

[2] Vita Salute Univ, Dept Psychiat, San Raffaele Inst, Milan, Italy

来源：

PSYCHIATRY RESEARCH | 2004年 / 127卷 / 03期

关键词：

major depressive disorder; MCP1; gene-2518; polymorphism;

D O I：

10.1016/j.psychres.2004.04.004

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We conducted a case-control association study of the monocyte chemoattractant protein-1 (MCPI) gene -2518 polymorphism in 90 patients with major depressive disorder. Genotyping was performed by polymerase chain reaction methods. We found significant differences in genotype and allele frequencies. The present study suggests that this polymorphism may confer a susceptibility to major depressive disorder in the Korean population. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

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页码：279 / 281

页数：3

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