Facile conversion of O-silyl protected sugars into their corresponding formates using POCl3 • DMF complex

被引：21

作者：

Andrade, MM ^{[1
]}

Barros, MT ^{[1
]}

机构：

[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, REQUIMTE,CQFB, P-2829516 Caparica, Portugal

来源：

TETRAHEDRON | 2004年 / 60卷 / 41期

关键词：

carbohydrates; Vilsmeier-Haack (V-H) complex; regio and chemoselective O-formylation;

D O I：

10.1016/j.tet.2004.07.056

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The direct O-formylation of two selectively protected sugar derivatives using the Vilsmeier-Haack (V-H) complex (POCl3DMF)-D-. was studied. Primary O-TBDMS and O-TBDPS ethers of sucrose, the most common disaccharide, underwent regio and chemoselective O-formylation with this formylating agent. This conversion was also studied with a monosaccharide analogue. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：9235 / 9243

页数：9