Utility and quality of autologous fresh frozen plasma and autologous fibrin glue for surgical patients

被引：4

作者：

Komatsu, F ^{[1
]}

Yoshida, S ^{[1
]}

机构：

[1] Tokyo Med & Dent Univ, Sch Med, Blood Transfus Serv, Bunkyo Ku, Tokyo 1138519, Japan

来源：

TRANSFUSION SCIENCE | 1999年 / 21卷 / 02期

关键词：

autologous blood product; fresh frozen plasma; fibrin glue; coagulation factor;

D O I：

10.1016/S0955-3886(99)00080-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The quality of autologous fresh frozen plasma and autologous fibrin glue prepared in our hospital was evaluated. The Auto-FFP was separated from whole blood or collected using a cell separator and the Auto-FG was then prepared from the Auto-FFP. The Auto-FFP showed significantly higher levels of fibrinogen, Factor-V and Factor-VIII than commercially available FFP. The Auto-FG contained approximately 10 times the concentration of fibrinogen, Factor-VIII, Factor-XIII, von Willbrand factor and fibronectin and 1.5 times that of alpha(2)-Plasminogen inhibitor compared to those of the Auto-FFP. When the Auto-FG was sprayed over diffusely bleeding sites from surgical wounds, hemostasis occurred within 5 s. These results suggest that Auto-FFP and Auto-FG may have sufficient utility and quality to reduce the use of allogeneic blood products. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：105 / 109

页数：5

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