Enantioselective addition of diethylzinc to aldehydes using 2-azanorbornylmethanols and 2-azanorbornylmethanethiol as a catalyst

被引：94

作者：

Nakano, H

Kumagai, N

Matsuzaki, H

Kabuto, C

Hongo, H

机构：

[1] TOHOKU COLL PHARMACEUT SCI,AOBA KU,SENDAI,MIYAGI 981,JAPAN

[2] TOHOKU UNIV,FAC SCI,DEPT CHEM,SENDAI,MIYAGI 980,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 09期

关键词：

ASYMMETRIC-SYNTHESIS; ORGANOZINC REAGENTS; ACID-DERIVATIVES; DIALKYLZINCS; ALCOHOLS; LIGANDS; BENZALDEHYDE; REDUCTION;

D O I：

10.1016/S0957-4166(97)00118-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Optically active 2-azanorbornylmethanols and 2-azanorbornylmethanethiol were prepared from ethyl(1S,3S,4R)-2-[(R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate and catalyzed the enantioselective addition of diethylzinc to aldehydes to give optically active secondary alcohols. (C) 1997 Elsevier Science Ltd.

引用

页码：1391 / 1401

页数：11

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