Analytical monitoring devices based on combined capillary electrophoresis and fluorescence

被引：6

作者：

Belen'kii, BG ^{[1
]}

Kurochkin, VE

Kozulin, RA

Zolotarev, VM

机构：

[1] Russian Acad Sci, Inst Analyt Instrumentat, St Petersburg 198103, Russia

[2] Tech Univ, St Petersburg State Inst Precis Mech & Opt, St Petersburg, Russia

来源：

JOURNAL OF OPTICAL TECHNOLOGY | 2002年 / 69卷 / 03期

关键词：

D O I：

10.1364/JOT.69.000191

中图分类号：

O43 [光学];

学科分类号：

070207 [光学]; 0803 [光学工程];

摘要：

This paper reviews the criteria for detecting individual molecules in liquids. It focuses on the detection of individual molecules by means of capillary electrophoresis and laser fluorimetry. It discusses the main experimental limitations and obstacles that make it hard to reliably detect individual molecules. It discusses the results of tests of the Nanofor device, fabricated at the Institute of Analytical Instrumentation, Russian Academy of Sciences, which uses original technical solutions to provide the conditions for high-sensitivity detection of fluorescing molecules in a capillary. (C) 2002 Optical Society of America.

引用

页码：191 / 197

页数：7

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