Fluorescence-enhanced, near infrared diagnostic imaging with contrast agents

被引：283

作者：

Sevick-Muraca, EM ^{[1
]}

Houston, JP ^{[1
]}

Gurfinkel, M ^{[1
]}

机构：

[1] Texas A&M Univ, Photon Migrat Lab, College Stn, TX 77845 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 05期

关键词：

D O I：

10.1016/S1367-5931(02)00356-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The deep tissue propagation of near-infrared (NIR) light between 700-900 nm offers new opportunities for diagnostic imaging when employing sensitive detection techniques and NIR excitable fluorescent agents that target and report disease and metabolism. Herein, we highlight approaches for illuminating tissues and monitoring the re-emitted fluorescence for tomographic reconstruction, strategies for developing fluorescent dye constructs, and clinical opportunities for fluorescence-enhanced NIR optical imaging.

引用

页码：642 / 650

页数：9

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