Transcription of the kinetoplastid spliced leader RNA gene

被引：38

作者：

Campbell, DA ^{[1
]}

Sturm, NR ^{[1
]}

Yu, MC ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA

来源：

PARASITOLOGY TODAY | 2000年 / 16卷 / 02期

关键词：

D O I：

10.1016/S0169-4758(99)01545-8

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

In recent years, much has been learned about the cis-elements controlling transcription of the kinetoplastid spliced lender (SL) RNA gene. The SL RNA gene contains the first 39 nucleotides that are trans-spliced on to all nuclear-derived mRNAs in these organisms. Transcription initiation is determined by two precisely spaced upstream elements and transcription termination is directed by the downstream poly-T tract, although the RNA polymerase responsible for SL RNA synthesis is still questioned. br this article, David Campbell, Nancy Sturm and Michael Yu review the field of kinetoplastid SL RNA gene transcription, address past proposals in light of current data and discuss some of the differences that appear in the literature.

引用

页码：78 / 82

页数：7

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