Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study)

被引：24

作者：

AboElsaad, Nayer S. ^{[2
]}

Soory, Mena ^{[1
]}

Gadalla, Laila M. A. ^{[2
]}

Ragab, Laila I. ^{[2
]}

Dunne, Stephen ^{[3
]}

Zalata, Khaled R. ^{[2
]}

Louca, Chris ^{[4
]}

机构：

[1] Kings Coll Dent Hosp, GKT Hosp, Kings Coll London Dent Inst, London SE5 9RW, England

[2] Mansoura Univ, Fac Dent, Dept Oral Med & Periodontol, Mansoura, Egypt

[3] Kings Coll London Dent Inst, Primary Dent Care Dept, London, England

[4] UCL Eastman Dent Inst, Eastman CPD, London, England

来源：

LASERS IN MEDICAL SCIENCE | 2009年 / 24卷 / 04期

关键词：

Bioactive glass; Bone healing; Diode laser; Low power laser; INFRARED-LASER; DIODE-LASER; IRRADIATION; THERAPY; REPAIR; TRAUMA; RATS; NM;

D O I：

10.1007/s10103-008-0590-y

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of 36 Wistar rats divided into two groups, each consisting of 18 rats. Group I was treated with bioactive glass plus laser irradiation. Group II was treated with graft material only. The animals were killed at 4 weeks, 8 weeks and 12 weeks postoperatively for histological examination. Laser irradiation had significantly accelerated bone healing at 4 weeks and 8 weeks in comparison with that at the sites not irradiated. However at 12 weeks, complete healing of the defects had occurred with no difference detected. Our results have confirmed the positive effect of soft laser in accelerating bone regeneration.

引用

页码：527 / 533

页数：7

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