Antigen 43, a phase-variable bipartite outer membrane protein, determines colony morphology and autoaggregation in Escherichia coli K-12

被引：109

作者：

Henderson, IR ^{[1
]}

Meehan, M ^{[1
]}

Owen, P ^{[1
]}

机构：

[1] UNIV DUBLIN TRINITY COLL, MOYNE INST PREVENT MED, DEPT MICROBIOL, DUBLIN 2, IRELAND

来源：

FEMS MICROBIOLOGY LETTERS | 1997年 / 149卷 / 01期

关键词：

antigen; 43; phase variation; autoaggregation; flu; Escherichia coli;

D O I：

10.1016/S0378-1097(97)00065-7

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The product controlling colony form variation and autoaggregation in Escherichia coli K-12 (the flu gene product) has been identified as the phase-variable, bipartite, outer membrane protein, termed antigen 43 (Ag43). Identification is based: (i) on complete correlation in authentic flu variants between colony morphology/autoaggregation and Ag43 expression as determined by colony and Western immunoblotting and immunofluorescence microscopy; and (ii) on the use of a specific probe to map the gene encoding Ag43 to a position (min 43) on the E. coli chromosome previously established for flu.

引用

页码：115 / 120

页数：6