An Integrated Microrobotic Platform for On-Demand, Targeted Therapeutic Interventions

被引：268

作者：

Fusco, Stefano ^{[1
]}

Sakar, Mahmut Selman ^{[1
]}

Kennedy, Stephen ^{[5
]}

Peters, Christian ^{[2
]}

Bottani, Rocco ^{[1
]}

Starsich, Fabian ^{[3
]}

Mao, Angelo ^{[5
]}

Sotiriou, Georgios A. ^{[4
]}

Pane, Salvador ^{[1
]}

Pratsinis, Sotiris E. ^{[3
]}

Mooney, David ^{[5
]}

Nelson, Bradley J. ^{[1
]}

机构：

[1] Swiss Fed Inst Technol, Inst Robot & Intelligent Syst, CH-8092 Zurich, Switzerland

[2] Swiss Fed Inst Technol, CH-8092 Zurich, Switzerland

[3] Swiss Fed Inst Technol, Particle Technol Lab, CH-8092 Zurich, Switzerland

[4] Harvard Univ, Sch Publ Hlth, Ctr Nanotechnol & Nanotoxicol, Boston, MA 02115 USA

[5] Harvard Univ, Sch Engn & Appl Sci, Wyss Inst Biologically Inspired Engn, Cambridge, MA 02318 USA

来源：

ADVANCED MATERIALS | 2014年 / 26卷 / 06期

基金：

美国国家卫生研究院; 欧洲研究理事会; 瑞士国家科学基金会;

关键词：

self-folding; responsive hydrogels; microrobotics; alginate microbeads; targeted drug and cell delivery; CELL SHEET RECOVERY; DRUG-DELIVERY; HYDROGEL BILAYERS; GRAPHENE OXIDE; RELEASE; MANIPULATION; FABRICATION; PRINCIPLES; ENDOSCOPY; SCAFFOLDS;

D O I：

10.1002/adma.201304098

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The presented microrobotic platform combines together the advantages of self-folding NIR light sensitive polymer bilayers, magnetic alginate microbeads, and a 3D manipulation system, to propose a solution for targeted, on-demand drug and cell delivery. First feasibility studies are presented together with the potential of the full design. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：952 / 957

页数：6

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