Asymmetric desymmetrization of dialkyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylates by a thermophilic esterase/lipase

被引：14

作者：

Kashima, Y ^{[1
]}

Liu, JX ^{[1
]}

Takenami, S ^{[1
]}

Niwayama, S ^{[1
]}

机构：

[1] Oklahoma State Univ, Dept Chem, Stillwater, OK 74078 USA

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(02)00228-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A thermophilic enzyme efficiently monohydrolyzed a series of meso diesters, dialkyl bicycle[2.2.1]hept-2,5-diene-2,3-dicarboxylates, in high chemical yields (72-98%) and high enantiomeric purities (>99% e.e.) in all the cases examined. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：953 / 956

页数：4

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