Encapsulation of single enzyme in nanogel with enhanced biocatalytic activity and stability

被引：276

作者：

Yan, Ming

Ge, Jun

Liu, Zheng ^{[1
]}

Ouyang, Pingkai

机构：

[1] Tsing Hua Univ, Dept Chem Engn, Beijing 100084, Peoples R China

[2] Nanjing Univ Technol, Coll Life Sci & Pharmaceut Engn, Nanjing 21009, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 34期

关键词：

D O I：

10.1021/ja064126t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Single protein encapsulated into nanogels with uniformed size and controllable shell thickness were prepared by surface acryloylation of a protein molecule followed by aqueous in situ polymerization. Compared to its free counterpart, the encapsulated protein exhibits similar biocatalytic behavior and significantly improved stability at high temperature and in the presence of organic solvent. Copyright © 2006 American Chemical Society.

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收藏

页码：11008 / 11009

页数：2

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