Buruli ulcer

被引：123

作者：

Portaels, Francoise ^{[1
]}

Silva, Manuel T. ^{[2
]}

Meyers, Wayne M. ^{[3
]}

机构：

[1] Inst Trop Med, Mycobacteriol Unit, B-2000 Antwerp, Belgium

[2] Inst Biol Mol & Celular, P-4150180 Oporto, Portugal

[3] Armed Forces Inst Pathol, Dept Environm & Infect Dis Sci, Washington, DC 20306 USA

来源：

CLINICS IN DERMATOLOGY | 2009年 / 27卷 / 03期

关键词：

MYCOBACTERIAL SKIN ULCERS; HOST IMMUNE-RESPONSE; PROTECTIVE EFFICACY; RISK-FACTORS; DNA VACCINE; WHOLE-BLOOD; BOVIS BCG; IN-VITRO; DISEASE; INFECTION;

D O I：

10.1016/j.clindermatol.2008.09.021

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Buruli ulcer is an indolent necrotizing disease of the skin, subcutaneous tissue, and bone that is caused by Mycobacterium ulcerans. Buruli ulcer is presently the third most common mycobacterial disease of humans, after tuberculosis and leprosy, and the least understood of the three. The disease remained largely ignored by many national public health programs, but more recently, it has been recognized as an emerging health problem, primarily due to its frequent disabling and stigmatizing complications. The contribution discusses various aspects of Buruli ulcer, including its geographic distribution, incidence, and prevalence; mode of transmission, pathogenesis, and immunity; clinical manifestations; laboratory diagnosis; differential clinical diagnosis; and treatment. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：291 / 305

页数：15

共 96 条

[71] CYTOTOXIC ACTIVITY OF MYCOBACTERIUM-ULCERANS [J].

READ, JK ;

HEGGIE, CM ;

MEYERS, WM ;

CONNOR, DH .

INFECTION AND IMMUNITY, 1974, 9 (06) :1114-1122

[72]

REVILL WDL, 1973, LANCET, V2, P873

[73] Murine salmonellosis studied by confocal Microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo [J].

RichterDahlfors, A ;

Buchan, AMJ ;

Finlay, BB .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (04) :569-580

[74] Contiguous spread of Mycobacterium ulcerans in Buruli ulcer lesions analysed by histopathology and real-time PCR quantification of mycobacterial DNA [J].

Rondini, S ;

Horsfield, C ;

Mensah-Quainoo, E ;

Junghanss, T ;

Lucas, S ;

Pluschke, G .

JOURNAL OF PATHOLOGY, 2006, 208 (01) :119-128

[75] Apoptosis in resolution of inflammation [J].

Savill, J .

JOURNAL OF LEUKOCYTE BIOLOGY, 1997, 61 (04) :375-380

[76] Aquatic insects and Mycobacterium ulcerans:: An association relevant to buruli ulcer control? [J].

Silva, Manuel T. ;

Portaels, Francoise ;

Pedrosa, Jorge .

PLOS MEDICINE, 2007, 4 (02) :229-231

[77] NEUTROPHIL MACROPHAGE COOPERATION IN THE HOST DEFENSE AGAINST MYCOBACTERIAL INFECTIONS [J].

SILVA, MT ;

NAZARE, M ;

SILVA, T ;

APPELBERG, R .

MICROBIAL PATHOGENESIS, 1989, 6 (05) :369-380

[78] Mycobacterium ulcerans infection:: control, diagnosis, and treatment [J].

Sizaire, V ;

Nackers, F ;

Comte, E ;

Portaels, F .

LANCET INFECTIOUS DISEASES, 2006, 6 (05) :288-296

[79] PRODUCTION AND PRELIMINARY INVESTIGATION OF BURULIN, A NEW SKIN-TEST REAGENT FOR MYCOBACTERIUM-ULCERANS INFECTION [J].

STANFORD, JL ;

REVILL, WDL ;

GUNTHORPE, WJ ;

GRANGE, JM .

JOURNAL OF HYGIENE, 1975, 74 (01) :7-16

[80] Susceptibility to development of Mycobacterium ulcerans disease:: review of possible risk factors [J].

Stienstra, Y ;

van der Graaf, WTA ;

Meerman, GJT ;

The, TH ;

de Leij, LF ;

van der Werf, TS .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2001, 6 (07) :554-562

← 1 2 3 4 5 6 7 8 9 10 →