Evaluation of a cefoxitin disk diffusion test for the routine detection of methicillin-resistant Staphylococcus aureus

被引：54

作者：

Boubaker, IBB ^{[1
]}

Ben Abbes, R ^{[1
]}

Ben Abdallah, H ^{[1
]}

Mamlouk, K ^{[1
]}

Mahjoubi, F ^{[1
]}

Kammoun, A ^{[1
]}

Hammami, A ^{[1
]}

Ben Redjeb, S ^{[1
]}

机构：

[1] Fac Med, Lab Resistance Antibiot, Tunis, Tunisia

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2004年 / 10卷 / 08期

关键词：

cefoxitin disk test; mecA; MRSA; susceptibility testing; Staphylococcus aureus;

D O I：

10.1111/j.1469-0691.2004.00919.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Two oxacillin disk methods were compared with a cefoxitin disk diffusion test for detection of methicillin-resistant Staphylococcus aureus (MRSA), with PCR for mecA as the reference method. When tested with 115 MRSA and 350 methicillin-susceptible S. aureus isolates, the cefoxitin disk test (specificity 100%, sensitivity 96.5%) was superior to the oxacillin disk methods (specificity 99.1%, sensitivity 90.4%). Testing with both oxacillin and cefoxitin disks would give better sensitivity (100%) than the cefoxitin test alone, but at the expense of specificity (99.1%). The cefoxitin disk test required no special test conditions and would improve the reliability of routine tests for detection of MRSA.

引用

收藏

页码：762 / 765

页数：4

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