Dipeptide binding in water by a de Novo designed guanidiniocarbonylpyrrole receptor

被引：104

作者：

Schmuck, C ^{[1
]}

Geiger, L ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 29期

关键词：

D O I：

10.1021/ja048587v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new dipeptide receptor 9, which was designed de novo based on theoretical calculations, efficiently binds dipeptides in water with Kass > 104 M-1 by a combination of ion pairing and hydrogen bonds as can be shown by UV-titration and NMR experiments. Copyright © 2004 American Chemical Society.

引用

页码：8898 / 8899

页数：2

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