Cognitive reserve

被引:2172
作者
Stern, Yaakov [1 ,2 ]
机构
[1] Columbia Univ, Cognit Neurosci Div, Taub Inst, Coll Phys & Surg,Dept Neurol, New York, NY 10027 USA
[2] Columbia Univ, Coll Phys & Surg, Dept Psychiat, New York, NY 10027 USA
关键词
Aging; Dementia; Epidemiolgy; FMRI; Neuroimaging; AGE-RELATED-CHANGES; EVENT-RELATED FMRI; ALZHEIMERS-DISEASE; LEISURE ACTIVITY; METABOLIC-RATES; OLDER PERSONS; HEALTHY-YOUNG; RISK-FACTORS; BRAIN SIZE; BLOOD-FLOW;
D O I
10.1016/j.neuropsychologia.2009.03.004
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The concept of reserve has been proposed to account for the disjunction between the degree of brain damage and its clinical outcome. This paper attempts to produce a coherent theoretical account the reserve in general and of cognitive reserve in particular. It reviews epidemiologic data supporting the concept of cognitive reserve, with a particular focus of its implications for aging and dementia. It then focuses on methodologic issues that are important when attempting to elucidate the neural underpinnings of cognitive reserve using imaging studies, and reviews some of our group's work in order to demonstrate these issues. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2015 / 2028
页数:14
相关论文
共 70 条
[1]   Predictors of cognitive change in older persons: MacArthur studies of successful aging [J].
Albert, MS ;
Savage, CR ;
Blazer, D ;
Jones, K ;
Berkman, L ;
Seeman, T ;
Rowe, JW .
PSYCHOLOGY AND AGING, 1995, 10 (04) :578-589
[2]   Reading ability, education, and cognitive status assessment among older adults in Harlem, New York City [J].
Albert, SM ;
Teresi, JA .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1999, 89 (01) :95-97
[3]  
Alexander GE, 1997, AM J PSYCHIAT, V154, P165
[4]   Cognitive reserve in neuropsychiatry [J].
Barnett, J. H. ;
Salmond, C. H. ;
Jones, P. B. ;
Sahakian, B. J. .
PSYCHOLOGICAL MEDICINE, 2006, 36 (08) :1053-1064
[5]   Education modifies the relation of AD pathology to level of cognitive function in older persons [J].
Bennett, DA ;
Wilson, RS ;
Schneider, JA ;
Evans, DA ;
de Leon, CFM ;
Arnold, SE ;
Barnes, LL ;
Bienias, JL .
NEUROLOGY, 2003, 60 (12) :1909-1915
[6]   Neural mechanisms of transient and sustained cognitive control during task switching [J].
Braver, TS ;
Reynolds, JR ;
Donaldson, DI .
NEURON, 2003, 39 (04) :713-726
[7]   Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis [J].
Brown, J ;
Cooper-Kuhn, CM ;
Kempermann, G ;
Van Praag, H ;
Winkler, J ;
Gage, FH ;
Kuhn, HG .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2003, 17 (10) :2042-2046
[8]   Age, education, and changes in the mini-mental state exam scores of older women: Findings from the nun study [J].
Butler, SM ;
Ashford, JW ;
Snowdon, DA .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1996, 44 (06) :675-681
[9]   Hemispheric asymmetry reduction in older adults: The HAROLD model [J].
Cabeza, R .
PSYCHOLOGY AND AGING, 2002, 17 (01) :85-100
[10]   Predicting cognitive impairment in high-functioning community-dwelling older persons: MacArthur studies of successful aging [J].
Chodosh, J ;
Reuben, DB ;
Albert, MS ;
Seeman, TE .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (06) :1051-1060