Synthetic applications of oxime-derived palladacycles as versatile catalysts in cross-coupling reactions

被引：63

作者：

Alonso, DA

Botella, L

Nájera, C

Pacheco, C

机构：

[1] Univ Alicante, Fac Ciencias, Dept Quim Organ, E-03080 Alicante, Spain

[2] Univ Alicante, ISO, E-03080 Alicante, Spain

来源：

SYNTHESIS-STUTTGART | 2004年 / 10期

关键词：

cross-coupling; palladacycles; Heck reaction; biaryls; alkynes;

D O I：

10.1055/s-2004-815992

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladacycles 1 and 2, derived from 4,4'-dichlorobenzophenone and 4-hydroxyacetophenone oximes, respectively, are very efficient and versatile pre-catalysts for a wide range of carbon-carbon bond coupling reactions such as, Mizoroki-Heck, Suzuki-Miyaura, Stille, Ullmann-type, Sonogashira, sila-Sonogashira, Glaser and acylation of alkynes under very low loading conditions in air and either in organic or aqueous solvents, employing reagent-grade chemicals. High yielding, general, and practical procedures for the palladium-catalyzed Mizoroki-Heck, Suzuki-Miyaura, Ullmann-type, Sonogashira and sila-Sonogashira reactions are described.

引用

页码：1713 / 1718

页数：6

共 51 条

[11] NC-palladacycles as highly effective cheap precursors for the phosphine-free Heck reactions [J].