Silk-inspired polymers and proteins

被引:69
作者
Hardy, John G. [1 ]
Scheibel, Thomas R. [1 ]
机构
[1] Univ Bayreuth, Lehrstuhl Biomat, D-95440 Bayreuth, Germany
关键词
biomimetic material; silk-inspired polymer; silkworm silk; spider silk; BOMBYX-MORI SILK; GENETICALLY-ENGINEERED SILK; SAMIA-CYNTHIA-RICINI; SPIDER-SILK; BETA-SHEETS; PERIODIC POLYPEPTIDES; STRUCTURAL-ANALYSIS; FIBROIN; COPOLYMERS; CRYSTALLIZATION;
D O I
10.1042/BST0370677
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The biocompatibility and biodegradability of natural silk fibres and the benign conditions under which they (with impressive mechanical properties) are produced represent a biomimetic ideal. This ideal has inspired people in both academia and industry to prepare silk-mimetic polymers and proteins by chemical and/or biotechnological means. in the present paper, we aim to give an overview of the design principles of such silk-inspired polymers/proteins, their processing into various materials morphologies, their mechanical and biological properties, and, finally, their technical and biomedical applications.
引用
收藏
页码:677 / 681
页数:5
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