Studies on novel synthetic methodologies, part 85.: Iodine as an efficient catalyst for one-pot multicomponent synthesis of β-acetamido ketones

被引：59

作者：

Das, Biswanath ^{[1
]}

Reddy, K. Ravinder ^{[1
]}

Ramu, R. ^{[1
]}

Thirupathi, P. ^{[1
]}

Ravikanth, B. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNLETT | 2006年 / 11期

关键词：

beta-acetamido ketone; iodine; multicomponent reaction;

D O I：

10.1055/s-2006-944208

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iodine efficiently catalyzes the three-component coupling of aromatic aldehydes, enolizable ketones or keto esters, and acetonitrile in the presence of acetyl chloride to afford beta-acetamido ketones in good yields at room temperature.

引用

页码：1756 / 1758

页数：3

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