Drivers of MERS-CoV transmission: what do we know?

被引：30

作者：

Al-Tawfiq, Jaffar A. ^{[1
,2
]}

Memish, Ziad A. ^{[3
,4
]}

机构：

[1] Johns Hopkins Aramco Healthcare, Dept Med, Dhahran, Saudi Arabia

[2] Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA

[3] Minist Hlth, Dept Med, Riyadh, Saudi Arabia

[4] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia

来源：

EXPERT REVIEW OF RESPIRATORY MEDICINE | 2016年 / 10卷 / 03期

关键词：

MERS-CoV; Coronavirus; Transmission; Prevention; Health Care Facilities; EAST RESPIRATORY SYNDROME; SYNDROME-CORONAVIRUS INFECTION; HEALTH-CARE WORKER; SAUDI-ARABIA; DROMEDARY CAMELS; FAMILY CLUSTER; SOUTH-KOREA; OUTBREAK; DISEASE; KINGDOM;

D O I：

10.1586/17476348.2016.1150784

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Middle East Respiratory Syndrome coronavirus (MERS-CoV) emerged in 2012 has since resulted in sporadic cases, intra-familial transmission and major outbreaks in healthcare settings. The clinical picture of MERS-CoV includes asymptomatic infections, mild or moderately symptomatic cases and fatal disease. Transmissions of MERS-CoV within healthcare settings are facilitated by overcrowding, poor compliance with basic infection control measures, unrecognized infections, the superspreaders phenomenon and poor triage systems. The actual contributing factors to the spread of MERS-CoV are yet to be systematically studied, but data to date suggest viral, host and environmental factors play a major role. Here, we summarize the known factors for the diverse transmission of MERS-CoV.

引用

页码：331 / 338

页数：8

共 86 条

[1] Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections, Tunisia, 2013 [J].

Abroug, Fekri ;

Slim, Amine ;

Ouanes-Besbes, Lamia ;

Kacem, Mohamed-Ali Hadj ;

Dachraoui, Fahmi ;

Ouanes, Islem ;

Lu, Xiaoyan ;

Tao, Ying ;

Paden, Clinton ;

Caidi, Hayat ;

Miao, Congrong ;

Al-Hajri, Mohammed Mohammed ;

Zorraga, Mokhtar ;

Ghaouar, Wissem ;

BenSalah, Afif ;

Gerber, Susan I. .

EMERGING INFECTIOUS DISEASES, 2014, 20 (09) :1527-1530

[2] Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description [J].

Al-Abdallat, Mohammad Mousa ;

Payne, Daniel C. ;

Alqasrawi, Sultan ;

Rha, Brian ;

Tohme, Rania A. ;

Abedi, Glen R. ;

Al Nsour, Mohannad ;

Iblan, Ibrahim ;

Jarour, Najwa ;

Farag, Noha H. ;

Haddadin, Aktham ;

Al-Sanouri, Tarek ;

Tamin, Azaibi ;

Harcourt, Jennifer L. ;

Kuhar, David T. ;

Swerdlow, David L. ;

Erdman, Dean D. ;

Pallansch, Mark A. ;

Haynes, Lia M. ;

Gerber, Susan I. .

CLINICAL INFECTIOUS DISEASES, 2014, 59 (09) :1225-1233

[3] A Case of Long-term Excretion and Subclinical Infection With Middle East Respiratory Syndrome Coronavirus in a Healthcare Worker [J].

Al-Gethamy, Manal ;

Corman, Victor M. ;

Hussain, Raheela ;

Al-Tawfiq, Jaffar A. ;

Drosten, Christian ;

Memish, Ziad A. .

CLINICAL INFECTIOUS DISEASES, 2015, 60 (06) :973-+

[4]

Al-Tawfiq Jaffar A, 2015, Hosp Pract (1995), V43, P158, DOI 10.1080/21548331.2015.1074029

[5] Middle East respiratory syndrome coronavirus in healthcare settings [J].

Al-Tawfiq, Jaffar A. ;

Perl, Trish M. .

CURRENT OPINION IN INFECTIOUS DISEASES, 2015, 28 (04) :392-396

[6] An update on Middle East respiratory syndrome: 2 years later [J].

Al-Tawfiq, Jaffar A. ;

Memish, Ziad A. .

EXPERT REVIEW OF RESPIRATORY MEDICINE, 2015, 9 (03) :327-335

[7] Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution [J].

Al-Tawfiq, Jaffar A. ;

Memish, Ziad A. .

TRENDS IN MICROBIOLOGY, 2014, 22 (10) :573-579

[8] Coronaviruses: severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus in travelers [J].

Al-Tawfiq, Jaffar A. ;

Zumla, Alimuddin ;

Memish, Ziad A. .

CURRENT OPINION IN INFECTIOUS DISEASES, 2014, 27 (05) :411-417

[9] Middle East Respiratory Syndrome Coronavirus: A Case-Control Study of Hospitalized Patients [J].

Al-Tawfiq, Jaffar A. ;

Hinedi, Kareem ;

Ghandour, Jihad ;

Khairalla, Hanan ;

Musleh, Samir ;

Ujayli, Alaa ;

Memish, Ziad A. .

CLINICAL INFECTIOUS DISEASES, 2014, 59 (02) :160-165

[10] Emerging respiratory viral infections: MERS-CoV and influenza [J].

Al-Tawfiq, Jaffar A. ;

Memish, Ziad A. .

LANCET RESPIRATORY MEDICINE, 2014, 2 (01) :23-25

← 1 2 3 4 5 6 7 8 9 →