A new route for isoquinolines catalyzed by palladium

被引:8
作者
Cho, Chan Sik [1 ]
Patel, Daksha B.
机构
[1] Kyungpook Natl Univ, Res Inst Ind Technol, Taegu 702701, South Korea
[2] Kyungpook Natl Univ, Dept Appl Chem, Taegu 702701, South Korea
关键词
alkenes; 3-bromopyridine-4-carbaldehyde; heck and aldol reactions; isoquinolines; palladium catalyst;
D O I
10.1016/j.molcata.2006.07.011
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
3-Bromopyridine-4-carbaldehyde is tethered with suitably electron withdrawing group substituted alkenes via Heck coupling followed by aldol reaction in dioxane at 150 degrees C under a catalytic system of Pd(OAc)(2)/PPh3/NaOAc to afford the corresponding isoquinolines in good yields. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:105 / 108
页数:4
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