Ionic and covalent copper(II)-based catalysts for Michael additions.: The mechanism

被引：41

作者：

Comelles, J

Moreno-Mañas, M

Pérez, E

Roglans, A

Sebastián, RM

Vallribera, A

机构：

[1] Univ Autonoma Barcelona, Dept Chem, E-08193 Barcelona, Spain

[2] Univ Girona, Dept Chem, Girona 17071, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 20期

关键词：

D O I：

10.1021/jo049373z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cu(SbF6)(2)-AdamBox and copper(II) bis-(5-tert-butylsalicylaldehydate) catalyze the Michael addition in neutral media. Mechanistic studies, based on UV-vis, IR, and electrospray ionization mass spectrometry (ESI-MS), suggest that copper enolates of the beta-dicarbonyl formed in situ are the active nucleophilic species.

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页码：6834 / 6842

页数：9

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