Adhere upright:: A switchblade-like extension of β2 integrins

被引:12
作者
Kinashi, Tatsuo [1 ]
机构
[1] Kansai Med Univ, Dept Mol Genet, Inst Biomed Sci, Moriguchi, Osaka 5708506, Japan
关键词
D O I
10.1016/j.immuni.2006.09.002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this issue of Immunity, Nishida et al., (2006) demonstrate a spectrum of dynamic conformation changes from a bent form to extended forms, in extracellular domains in alpha(X)beta(2) and alpha(L)beta(2) upon separation of the alpha and beta subunits, providing structural evidence for activation of leukocyte integrins.
引用
收藏
页码:521 / 522
页数:2
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