Motor neuron specification in worms, flies and mice: conserved and 'lost' mechanisms

被引：63

作者：

Thor, S

Thomas, JB

机构：

[1] Harvard Univ, Sch Med, Dept Neurobiol, Boston, MA 02115 USA

[2] Salk Inst Biol Studies, Mol Neurobiol Lab, San Diego, CA 92186 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2002年 / 12卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-437X(02)00340-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Motor neuron differentiation has been studied intensively in both invertebrates and vertebrates in recent years. These studies have led to the identification of several key regulatory genes acting to generate motor neurons and to specify their subclass identities. By comparing findings from Caenorhabditis elegans, Drosophila and vertebrate model systems, it is apparent that both evolutionarily conserved and non-conserved mechanisms are used.

引用

收藏

页码：558 / 564

页数：7

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