Universal epitopes of influenza virus hemagglutinins?

被引:46
作者
Wang, Taia T. [1 ]
Palese, Peter [1 ]
机构
[1] Mt Sinai Sch Med, Dept Microbiol, New York, NY 10029 USA
来源
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2009年 / 16卷 / 03期
关键词
ANTIBODIES; NEUTRALIZATION; REPERTOIRE; GENE;
D O I
10.1038/nsmb.1574
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The influenza virus has proved an elusive target in the development of broadly protective vaccines. A new study identifies an antibody with broad neutralizing activity against influenza viruses of different subtypes. The antibody recognizes a highly conserved region on the viral hemagglutinin that may be targeted to prevent infection. (c) 2009 Nature America, Inc. All rights reserved.
引用
收藏
页码:233 / 234
页数:2
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