Synthesis of (2R)-2-bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid

被引：32

作者：

Manthey, MK ^{[1
]}

GonzalezBello, C ^{[1
]}

Abell, C ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CTR MOL RECOGNIT,CAMBRIDGE CB2 1EW,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 05期

关键词：

D O I：

10.1039/a606104d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(2R)-2-Bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid dagger have each been synthesised in six steps from quinic acid via the common intermediate 6, The syntheses exploit the selective protection of the 4-hydroxy group of the quinic acid lactone 3 with tert-butyldimethylsilyl chloride.

引用

页码：625 / 628

页数：4

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