Gold nanoparticles for regulation of cell function and behavior

被引：93

作者：

Bodelon, Gustavo ^{[1
,2
]}

Costas, Celina ^{[1
,2
]}

Perez-Juste, Jorge ^{[1
,2
]}

Pastoriza-Santos, Isabel ^{[1
,2
]}

Liz-Marzan, Luis M. ^{[1
,2
,3
,4
,5
]}

机构：

[1] Univ Vigo, Dept Quim Fis, Vigo 36310, Spain

[2] Univ Vigo, CINBIO, Vigo 36310, Spain

[3] CIC biomaGUNE, Bionanoplasmon Lab, Paseo Miramon 182, Donostia San Sebastian 20014, Spain

[4] Basque Fdn Sci, Ikerbasque, Bilbao 48013, Spain

[5] Biomed Res Networking Ctr Bioengn Biomat & Nanome, Donostia San Sebastian 20014, Spain

来源：

NANO TODAY | 2017年 / 13卷

基金：

欧洲研究理事会;

关键词：

Gold nanoparticles; Nanostructured materials; Cell behavior; Cell function; Cellular receptor; Cell signaling; Plasmonics; LSPR; Optothermal; Nanotechnology; HIGH-DENSITY-LIPOPROTEIN; EXTRACELLULAR-MATRIX; NANOSCALE STRATEGIES; METAL NANOPARTICLES; SIGNALING NETWORKS; NEURAL STIMULATION; CANCER-CELLS; ANGIOGENESIS; GROWTH; NANORODS;

D O I：

10.1016/j.nantod.2016.12.014

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

The cell possesses the remarkable ability to perceive and process chemical and physical stimuli, which in turn modulate cellular behavior. One of the great wonders about nanotechnology is that it enables the fabrication of tools on the same length scale as biomolecules, thereby providing us with a unique handle for characterizing and controlling basic cellular processes. Owing to their tunable size and shape dependent physical properties, biocompatibility and facile surface modification, gold nanoparticles become potentially powerful tools to probe fundamental aspects of cell biology. Consequently, innovative approaches based on gold nanoparticles are under development toward the manipulation of cell function and improvement of techniques currently used in biomedicine and biotechnology. In this review we provide an overview of recent applications based on gold nanoparticles and nanostructured materials for the modulation of cellular activity and behavior, mediated by their interactions with cell surface receptors. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：40 / 60

页数：21

共 180 条

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Dynamic Imaging of Molecular Assemblies in Live Cells Based on Nanoparticle Plasmon Resonance Coupling [J].