Microchip-based high-throughput screening analysis of combinatorial libraries

被引：62

作者：

Khandurina, J ^{[1
]}

Guttman, A ^{[1
]}

机构：

[1] Torrey Mesa Res Inst, San Diego, CA 92121 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 03期

关键词：

D O I：

10.1016/S1367-5931(02)00323-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In recent years, there have been significant advances in biochemical assay miniaturization and integration of microchip-based technologies with combinatorial library screening for high-throughput and large-scale applications. Small-molecule microarrays, protein arrays and cell-based arrays and conventional DNA arrays as well as microfluidic approaches in HTS are discussed in this review.

引用

页码：359 / 366

页数：8