Mineralocorticoid action

被引：92

作者：

Rogerson, FM ^{[1
]}

Fuller, PJ ^{[1
]}

机构：

[1] Prince Henrys Inst Med Res, Clayton, Vic 3168, Australia

来源：

STEROIDS | 2000年 / 65卷 / 02期

关键词：

aldosterone; receptor; sodium channel; sodium transport;

D O I：

10.1016/S0039-128X(99)00087-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The physiology of mineralocorticoid action, particularly with respect to epithelial sodium transport, is well defined. A full understanding of the molecular basis of mineralocorticoid action has however proven to be more elusive. In the last decade insights into structural and functional aspects of the mineralocorticoid receptor combined with emerging details of the components of the mediators of the sodium flux has resulted in a clearer picture. This review focuses on two aspects of these new developments; the mineralocorticoid receptor and putative aldosterone induced proteins. (C) 2000 Elsevier Science Inc. All rights reserved.

引用

页码：61 / 73

页数：13

共 131 条

[91] SECONDARY EFFECT OF ALDOSTERONE ON NA-K ATPASE ACTIVITY IN THE RABBIT CORTICAL COLLECTING TUBULE [J].

PETTY, KJ ;

KOKKO, JP ;

MARVER, D .

JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (06) :1514-1521

[92] Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the β-subunit of the amiloride-sensitive epithelial sodium channel [J].

PRadervand, S ;

Barker, PM ;

Wang, Q ;

Ernst, SA ;

Beermann, F ;

Grubb, BR ;

Burnier, M ;

Schmidt, A ;

Bindels, RJM ;

Gatzy, JT ;

Rossier, BC ;

Hummler, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (04) :1732-1737

[93]

RAFESTINOBLIN ME, 1991, COLLOQ INSE, V215, P55

[94] LOCALIZATION AND REGULATION BY STEROIDS OF THE ALPHA-SUBUNITS, BETA-SUBUNITS AND GAMMA-SUBUNITS OF THE AMILORIDE-SENSITIVE NA+ CHANNEL IN COLON, LUNG AND KIDNEY [J].

RENARD, S ;

VOILLEY, N ;

BASSILANA, F ;

LAZDUNSKI, M ;

BARBRY, P .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1995, 430 (03) :299-307

[95] TRANSACTIVATION AND SYNERGISTIC PROPERTIES OF THE MINERALOCORTICOID RECEPTOR - RELATIONSHIP TO THE GLUCOCORTICOID RECEPTOR [J].

RUPPRECHT, R ;

ARRIZA, JL ;

SPENGLER, D ;

REUL, JMHM ;

EVANS, RM ;

HOLSBOER, F ;

DAMM, K .

MOLECULAR ENDOCRINOLOGY, 1993, 7 (04) :597-603

[96] Guanine nucleotide binding proteins in cultured renal epithelia: studies with pertussis toxin and aldosterone [J].

Sariban-Sohraby, S ;

Svoboda, M ;

Mies, F .

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 1999, 276 (01) :F10-F17

[97] GUANINE NUCLEOTIDE-DEPENDENT CARBOXYMETHYLATION - A PATHWAY FOR ALDOSTERONE MODULATION OF APICAL NA+ PERMEABILITY IN EPITHELIA [J].

SARIBANSOHRABY, S ;

FISHER, RS .

KIDNEY INTERNATIONAL, 1995, 48 (04) :965-969

[98] IMMUNOLOCALIZATION OF MINERALOCORTICOID RECEPTOR IN HUMAN KIDNEY, PANCREAS, SALIVARY, MAMMARY AND SWEAT GLANDS - A LIGHT AND ELECTRON-MICROSCOPIC IMMUNOHISTOCHEMICAL STUDY [J].

SASANO, H ;

FUKUSHIMA, K ;

SASAKI, I ;

MATSUNO, S ;

NAGURA, H ;

KROZOWSKI, ZS .

JOURNAL OF ENDOCRINOLOGY, 1992, 132 (02) :305-&

[99] Glucocorticoid induction of epithelial sodium channel expression in lung and renal epithelia occurs via trans-activation of a hormone response element in the 5′-flanking region of the human epithelial sodium channel α subunit gene [J].

Sayegh, R ;

Auerbach, SD ;

Li, X ;

Loftus, RW ;

Husted, RF ;

Stokes, JB ;

Thomas, CP .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (18) :12431-12437

[100] STEROID-HORMONE STIMULATION OF NA+ TRANSPORT IN A6 CELLS IS MEDIATED VIA GLUCOCORTICOID RECEPTORS [J].

SCHMIDT, TJ ;

HUSTED, RF ;

STOKES, JB .

AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 264 (04) :C875-C884

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