Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168

被引：71

作者：

Tosato, V

Albertini, AM

Zotti, M

Sonda, S

Bruschi, CV

机构：

[1] ITALTBS RIC SRL,AREA SCI PK,I-34012 TRIESTE,ITALY

[2] INT CTR GENET ENGN & BIOTECHNOL,MICROBIOL GRP,I-34012 TRIESTE,ITALY

[3] UNIV PAVIA,DIPARTIMENTO GENET & MICROBIOL A BUZZATI TRAVERS,I-27100 PAVIA,ITALY

来源：

MICROBIOLOGY-UK | 1997年 / 143卷

关键词：

antifungal antibiotic; Bacillus subtilis; fengycin; lipopeptide synthetase;

D O I：

10.1099/00221287-143-11-3443

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A 15 kb DNA fragment from the Bacillus subtilis chromosome between citB and ppsC has been sequenced, and new ORFs encoding putative enzymes involved in lipopolypeptide synthesis, which complete a partial operon previously reported, and a new set of enzymes responsible for lipid metabolism have been identified. From the analysis of DNA sequence homology of the fragment it was deduced that these new peptide synthetase genes are part of an operon for the biosynthesis of the fungicide fengycin.

引用

页码：3443 / 3450

页数：8

共 34 条

[11]

KRATZSCHMAR J, 1989, J BACTERIOL, V171, P5422

[12] ITURINS, A SPECIAL-CLASS OF PORE-FORMING LIPOPEPTIDES - BIOLOGICAL AND PHYSICOCHEMICAL PROPERTIES [J].