Val66met polymorphism and serum brain-derived neurotrophic factor levels in bipolar disorder

被引：44

作者：

Tramontina, J.

Frey, B. N.

Andreazza, A. C.

Zandona, M.

Santin, A.

Kapczinski, F. ^{[1
]}

机构：

[1] Univ Fed Rio Grande Sul, Programa Posgrad Ciencias Med, Porto Alegre, RS, Brazil

[2] Hosp Clin Porto Alegre, Ctr Pesquisas, Programa Transtorno Bipolar, Porto Alegre, RS, Brazil

[3] Univ Fed Rio Grande Sul, Inst Ciencias Bas Saude, Dept Bioquim, Porto Alegre, RS, Brazil

[4] Univ Fed Rio Grande Sul, Dept Genet, Porto Alegre, RS, Brazil

来源：

MOLECULAR PSYCHIATRY | 2007年 / 12卷 / 03期

关键词：

D O I：

10.1038/sj.mp.4001941

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：230 / 231

页数：2

共 10 条

[1] Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons [J].

Chen, ZY ;

Patel, PD ;

Sant, G ;

Meng, CX ;

Teng, KK ;

Hempstead, BL ;

Lee, FS .

JOURNAL OF NEUROSCIENCE, 2004, 24 (18) :4401-4411

[2] The genetics of schizophrenia and bipolar disorder: dissecting psychosis [J].

Craddock, N ;

O'Donovan, MC ;

Owen, MJ .

JOURNAL OF MEDICAL GENETICS, 2005, 42 (03) :193-204

[3] Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes [J].

Cunha, Angelo B. M. ;

Frey, Benicio N. ;

Andreazza, Ana C. ;

Goi, Julia D. ;

Rosa, Adriane R. ;

Goncalves, Carlos A. ;

Santin, Aida ;

Kapczinski, Flavio .

NEUROSCIENCE LETTERS, 2006, 398 (03) :215-219

[4] The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function [J].

Egan, MF ;

Kojima, M ;

Callicott, JH ;

Goldberg, TE ;

Kolachana, BS ;

Bertolino, A ;

Zaitsev, E ;

Gold, B ;

Goldman, D ;

Dean, M ;

Lu, B ;

Weinberger, DR .

CELL, 2003, 112 (02) :257-269

[5] Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients [J].

Gonul, AS ;

Akdeniz, F ;

Taneli, F ;

Donat, O ;

Eker, Ç ;

Vahip, S .

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2005, 255 (06) :381-386

[6] Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder - Case-control study of over 3000 individuals from the UK [J].

Green, EK ;

Raybould, R ;

MacGregor, S ;

Hyde, S ;

Young, AH ;

O'Donovan, MC ;

Owen, MJ ;

Kirov, G ;

Jones, L ;

Jones, I ;

Craddock, N .

BRITISH JOURNAL OF PSYCHIATRY, 2006, 188 :21-25

[7] Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets [J].

Karege, F ;

Schwald, M ;

Cisse, M .

NEUROSCIENCE LETTERS, 2002, 328 (03) :261-264

[8]

MACHADOVIEIRA R, IN PRESS BIOL PSYCHI

[9] The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study [J].

Neves-Pereira, M ;

Mundo, E ;

Muglia, P ;

King, N ;

Macciardi, F ;

Kennedy, JL .

AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (03) :651-655

[10] Illness-specific association of val66met BDNF polymorphism with performance on Wisconsin Card Sorting Test in bipolar mood disorder [J].

Rybakowski, JK ;

Borkowska, A ;

Skibinska, M ;

Hauser, J .

MOLECULAR PSYCHIATRY, 2006, 11 (02) :122-124

← 1 →