High-Photoluminescence-Yield Gold Nanocubes: For Cell Imaging and Photothermal Therapy

被引:232
作者
Wu, Xi [2 ]
Ming, Tian [1 ]
Wang, Xin [3 ]
Wang, Peinan [4 ]
Wang, Jianfang [1 ]
Chen, Jiyao [2 ]
机构
[1] Chinese Univ Hong Kong, Dept Phys, Shatin, Hong Kong, Peoples R China
[2] Fudan Univ, Surface Phys Lab, Natl Key Lab, Dept Phys, Shanghai 200433, Peoples R China
[3] Fudan Univ, Dept Microbiol & Microbial Engn, Sch Life Sci, Shanghai 200433, Peoples R China
[4] Fudan Univ, Dept Opt Sci & Engn, Shanghai 200433, Peoples R China
基金
中国国家自然科学基金;
关键词
gold nanocubes; photoluminescence; cell imaging; photothermal therapy; 2-PHOTON-INDUCED PHOTOLUMINESCENCE; METAL NANOPARTICLES; NANORODS; LUMINESCENCE; FLUORESCENCE; ABSORPTION; SIZE; ENHANCEMENT; TEMPERATURE; BIPYRAMIDS;
D O I
10.1021/nn901064m
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Gold nanocubes demonstrate unique optical properties of the high photoluminescence (PL) quantum yield and a remarkably enhanced extinction band at 544 nm. The 4 X 10(-2) PL yield, which is about 200 times higher than that of gold nanorods, allows gold nanocubes to be successfully used in cell imaging of human liver cancer cells (QGY) and human embryo kidney cells (293T) with a common method of single-photon excitation. The high extinction coefficients of gold nanocubes also facilitate them carrying out the photothermal therapy of QGY and 293T cells, showing similar photokilling efficiency as compared to gold nanorods.
引用
收藏
页码:113 / 120
页数:8
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