NK cell receptors in antiviral immunity

被引：31

作者：

Moser, JM ^{[1
]}

Byers, AM ^{[1
]}

Lukacher, AE ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Pathol, Atlanta, GA 30322 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(02)00357-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8(+) up T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8(+) T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.

引用

页码：509 / 516

页数：8

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