NK cell receptors in antiviral immunity

被引:31
作者
Moser, JM [1 ]
Byers, AM [1 ]
Lukacher, AE [1 ]
机构
[1] Emory Univ, Sch Med, Dept Pathol, Atlanta, GA 30322 USA
关键词
D O I
10.1016/S0952-7915(02)00357-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8(+) up T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8(+) T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.
引用
收藏
页码:509 / 516
页数:8
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