Heck reactions using segmented flow conditions

被引：85

作者：

Ahmed-Omer, Batoul ^{[1
,2
]}

Barrow, David A. ^{[1
]}

Wirth, Thomas ^{[2
]}

机构：

[1] Cardiff Univ, Cardiff Sch Engn, metaFAB Lab Appl Microsyst, Cardiff CF23 3AA, S Glam, Wales

[2] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 26期

基金：

英国工程与自然科学研究理事会;

关键词：

CROSS-COUPLING REACTIONS; VISCOSITY IONIC LIQUID; CARBON BOND FORMATION; CHEMICAL-SYNTHESIS; FLUID-FLOW; PALLADIUM; CATALYSIS; MICROREACTORS; ARYLATION; HALIDES;

D O I：

10.1016/j.tetlet.2009.02.133

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various Heck couplings have been carried out using segmented flow conditions to accelerate the reactions. Aryl iodides and aryl bromides as well as anilines in diazonium-type Heck reactions have been used Successfully. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：3352 / 3355

页数：4

共 44 条

[1] Enhancement of reaction rates by segmented fluid flow in capillary scale reactors [J].

Ahmed, Batoul ;

Barrow, David ;

Wirth, Thomas .

ADVANCED SYNTHESIS & CATALYSIS, 2006, 348 (09) :1043-1048

[2]

Ahmed-Omer B., 2008, Microreactors in Organic Synthesis and Catalysis, P122

[3] Effect of segmented fluid flow, sonication and phase transfer catalysis on biphasic reactions in capillary microreactors [J].

Ahmed-Omer, Batoul ;

Barrow, David ;

Wirth, Thomas .

CHEMICAL ENGINEERING JOURNAL, 2008, 135 (S280-S283) :S280-S283

[4] Advanced organic synthesis using microreactor technology [J].

Ahmed-Omer, Batoul ;

Brandt, Johan C. ;

Wirth, Thomas .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2007, 5 (05) :733-740

[5] Non-conventional methodologies for transition-metal catalysed carbon-carbon coupling: a critical overview. Part 1: The Heck reaction [J].

Alonso, F ;

Beletskaya, IP ;

Yus, M .

TETRAHEDRON, 2005, 61 (50) :11771-11835

[6] FLUORESCENCE PROPERTIES OF 2,3-DIARYLINDENES [J].

ANSTEAD, GM ;

KATZENELLENBOGEN, JA .

JOURNAL OF PHYSICAL CHEMISTRY, 1988, 92 (22) :6249-6258

[7] The heck reaction as a sharpening stone of palladium catalysis [J].

Beletskaya, IP ;

Cheprakov, AV .

CHEMICAL REVIEWS, 2000, 100 (08) :3009-3066

[8] Comparison of activity and selectivity of various metal-TPPTS complex catalysts in ethylene glycol - Toluene biphasic Heck vinylation reactions of iodobenzene [J].

Bhanage, BM ;

Zhao, FG ;

Shirai, M ;

Arai, M .

TETRAHEDRON LETTERS, 1998, 39 (51) :9509-9512

[9] Application of a new combination of palladium and CaCO3 for an aerobic heck reaction using arenediazonium-salts [J].

Brunner, H ;

de Courcy, NLC ;

Genêt, JP .

TETRAHEDRON LETTERS, 1999, 40 (26) :4815-4818

[10] Silica-supported bidentate arsine palladium(0) complex: a highly active and stereoselective catalyst for arylation of conjugated alkenes [J].

Cai, MZ ;

Huang, YZ ;

Zhao, H ;

Song, CS .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2003, 682 (1-2) :20-25

← 1 2 3 4 5 →