Increasing the Scope of Palladium-Catalyzed Cyanations of Aryl Chlorides

被引：84

作者：

Schareina, Thomas ^{[1
]}

Jackstell, Ralf ^{[1
]}

Schulz, Thomas ^{[1
]}

Zapf, Alexander ^{[1
]}

Cotte, Alain ^{[2
]}

Gotta, Matthias ^{[2
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

[2] Saltigo GmbH, D-51369 Leverkusen, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2009年 / 351卷 / 04期

关键词：

aromatic substitution; aryl halides; C-C coupling; cyanides; palladium; CROSS-COUPLING REACTIONS; POTASSIUM HEXACYANOFERRATE(II); C-N; HETEROARYL CHLORIDES; CONVENIENT PROCEDURE; AMINATION REACTIONS; ACTIVE CATALYST; HALIDES; BROMIDES; SYSTEM;

D O I：

10.1002/adsc.200800733

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An improved protocol for the palladium-catalyzed cyanation of electron-rich aryl chlorides with potassium ferrocyanide {K-4[Fe(CN)(6)]} is presented. Compared to previous procedures the substrate scope is significantly broadened.

引用

页码：643 / 648

页数：6

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