Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: The Alzhemedtm (Tramiprosate) experience

被引：27

作者：

Saumier, D. ^{[1
]}

Aisen, P. S. ^{[2
]}

Gauthier, S. ^{[3
]}

Vellas, B. ^{[4
]}

Ferris, S. H. ^{[5
,6
]}

Duong, A. ^{[1
]}

Suhy, J. ^{[7
]}

Oh, J. ^{[7
]}

Lau, W. ^{[7
]}

Garceau, D. ^{[8
]}

Haine, D. ^{[9
]}

Sampalis, J. ^{[10
]}

机构：

[1] BELLUS Hlth Inc, Laval, PQ H7V 4A7, Canada

[2] Univ Calif San Diego, La Jolla, CA 92093 USA

[3] McGill Ctr Studies Aging, Verdun, PQ H4H 1R3, Canada

[4] Univ Toulouse, INSERM, U558, Ctr Hosp Univ,Alzheimer Dis Res & Clin Ctr, Toulouse, France

[5] NYU, Sch Med, New York, NY 10016 USA

[6] Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA

[7] Synarc Inc, San Francisco, CA 94105 USA

[8] OVOS Nat Hlth Inc, Laval, PQ H7V 4A7, Canada

[9] JSS Med Res, Westmount, PQ H3Z 1R7, Canada

[10] McGill Univ, Div Clin Epidemiol, Res Inst, McGill Univ Hlth Ctr,Royal Victoria Hosp, Montreal, PQ H3A 1A1, Canada

来源：

JOURNAL OF NUTRITION HEALTH & AGING | 2009年 / 13卷 / 04期

关键词：

HIPPOCAMPAL ATROPHY; ENTORHINAL CORTEX; AMYLOID-BETA; IMPAIRMENT; DIAGNOSIS; AMYGDALA; PHASE; AGE;

D O I：

10.1007/s12603-009-0047-4

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

[No abstract available]

引用

页码：370 / 372

页数：3

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