Depth-resolved fluorescence spectroscopy reveals layered structure of tissue

被引：55

作者：

Wu, YC ^{[1
]}

Xi, P

Qu, JAY

Cheung, TH

Yu, MY

机构：

[1] Hong Kong Univ Sci & Technol, Dept Elect & Elect Engn, Clear Water Bay, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Obstet & Gynecol, Shatin, Hong Kong, Peoples R China

来源：

OPTICS EXPRESS | 2004年 / 12卷 / 14期

关键词：

D O I：

10.1364/OPEX.12.003218

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A confocal fluorescence spectroscopy system is instrumented to study depth-resolved autofluorescence in biological tissue. The system provides the capability of optical sectioning with the maximal detection depth up to 120 mum in the examined tissue samples. It was found that the topmost keratinizing epithelial layer produces strong fluorescence similar to collagen. The fluorescence signal from epithelial tissue between the keratinizing layer and stroma can be well resolved. The study results show that depth-resolved fluorescence spectroscopy has the potential to provide more accurate information for the diagnosis of tissue pathology. (C) 2004 Optical Society of America.

引用

页码：3218 / 3223

页数：6

共 13 条

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