Polarized fluorescence spectroscopy of human tissues

被引:21
作者
Ghosh, N [1 ]
Majumder, SK [1 ]
Gupta, PK [1 ]
机构
[1] Ctr Adv Technol, Biomed Applicat Sect, Indore 452013, India
关键词
D O I
10.1364/OL.27.002007
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report the results of a study carried out to investigate the effect of blood absorption on polarized and unpolarized fluorescence from resected tissue samples and tissue phantoms, The signatures of blood absorption were found to be significantly smaller in polarized fluorescence than in unpolarized fluorescence spectra. The reduced effect of blood absorption on polarized fluorescence also leads to reduced site-to-site variability in polarized fluorescence intensity and line shape compared with unpolarized fluorescence. (C) 2002 Optical Society of America.
引用
收藏
页码:2007 / 2009
页数:3
相关论文
共 9 条
[1]   DEPOLARIZATION OF MULTIPLY SCATTERED WAVES BY SPHERICAL DIFFUSERS - INFLUENCE OF THE SIZE PARAMETER [J].
BICOUT, D ;
BROSSEAU, C ;
MARTINEZ, AS ;
SCHMITT, JM .
PHYSICAL REVIEW E, 1994, 49 (02) :1767-1770
[2]  
Bohren C. F., 1998, ABSORPTION SCATTERIN
[3]   Fluorescence depolarization in a scattering medium: Effect of size parameter of a scatterer [J].
Ghosh, N ;
Majumder, SK ;
Gupta, PK .
PHYSICAL REVIEW E, 2002, 65 (02) :1-026608
[4]   Measurement of optical transport properties of normal and malignant human breast tissue [J].
Ghosh, N ;
Mohanty, SK ;
Majumder, SK ;
Gupta, PK .
APPLIED OPTICS, 2001, 40 (01) :176-184
[5]  
Lackowicz J.R., 2006, PRINCIPLES FLUORESCE
[6]   Depolarization of autofluorescence from malignant and normal human breast tissues [J].
Mohanty, SK ;
Ghosh, N ;
Majumder, SK ;
Gupta, PK .
APPLIED OPTICS, 2001, 40 (07) :1147-1154
[7]   Fluorescence spectroscopy of neoplastic and non-neoplastic tissues [J].
Ramanujam, N .
NEOPLASIA, 2000, 2 (1-2) :89-117
[8]   PULSED AND CW LASER FLUORESCENCE-SPECTRA FROM CANCEROUS, NORMAL, AND CHEMICALLY TREATED NORMAL HUMAN-BREAST AND LUNG TISSUES [J].
TANG, GC ;
PRADHAN, A ;
SHA, W ;
CHEN, J ;
LIU, CH ;
WAHL, SJ ;
ALFANO, RR .
APPLIED OPTICS, 1989, 28 (12) :2337-2342
[9]  
Wagnieres GA, 1998, PHOTOCHEM PHOTOBIOL, V68, P603