MR and CT Monitoring of Recanalization, Reperfusion, and Penumbra Salvage Everything That Recanalizes Does Not Necessarily Reperfuse!

被引：80

作者：

Soares, Bruno P. ^{[1
]}

Chien, Jeffrey D. ^{[1
]}

Wintermark, Max ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Radiol, Neuroradiol Sect, San Francisco, CA 94143 USA

来源：

STROKE | 2009年 / 40卷 / 03期

关键词：

brain infarction; brain ischemia; cerebral infarct; CT; magnetic resonance; neuroradiology; reprefusion; tPA; ACUTE ISCHEMIC-STROKE; NO-REFLOW; DESMOTEPLASE; EFFICACY; SAFETY; TRIAL;

D O I：

10.1161/STROKEAHA.108.526814

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Revascularization therapies for acute stroke patients aim to rescue the ischemic penumbra by restoring the patency of the occluded artery ("recanalization") and the downstream capillary blood flow ("reperfusion"). This article reviews the definition of recanalization and reperfusion used in stroke clinical trials and their limitations and proposes a study design to determine the relative importance of recanalization, reperfusion, and collateral flow in evaluating the efficacy of revascularization therapies for acute ischemic stroke. (Stroke. 2009;40[suppl 1]:S24-S27.)

引用

页码：S24 / S27

页数：4

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