Using a core-sheath distribution of surface chemistry through 3D tissue engineering scaffolds to control cell ingress

被引：80

作者：

Barry, John J. A.

Howard, Daniel

Shakesheff, Kevin M.

Howdle, Steve M.

Alexander, Morgan R.

机构：

[1] Univ Nottingham, Sch Pharm, Lab Biophys & Surface Anal, Nottingham NG7 2RD, England

[2] Univ Nottingham, Sch Pharm, Tissue Engn Grp, Nottingham NG7 2RD, England

[3] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 11期

关键词：

D O I：

10.1002/adma.200502719

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A core/sheath distribution of cell-adhesive and non-cell-adhesive surface coatings is produced in porous biodegradable poly(D,L-lactic acid) discs using sequential plasma polymerization. The figure and cover show an X-ray micro-computed tomography image of a section of a 10 mm diameter, 4 mm thick scaffold where fibroblast cells (shown in red) have been encouraged by the surface chemistry to penetrate to the scaffold core.

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页码：1406 / +

页数：6

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