Differential Binding Profiles of StpA in Wild-Type and hns Mutant Cells: a Comparative Analysis of Cooperative Partners by Chromatin Immunoprecipitation-Microarray Analysis

被引：49

作者：

Uyar, Ebru

Kurokawa, Ken ^{[2
]}

Yoshimura, Mika

Ishikawa, Shu

Ogasawara, Naotake ^{[1
]}

Oshima, Taku

机构：

[1] Nara Inst Sci & Technol, Dept Bioinformat & Genom, Grad Sch Informat Sci, Nara 6300101, Japan

[2] Tokyo Inst Technol, Grad Sch Biol Informat, Yokohama, Kanagawa 2268503, Japan

来源：

JOURNAL OF BACTERIOLOGY | 2009年 / 191卷 / 07期

关键词：

PROTEIN H-NS; HISTONE-LIKE PROTEINS; ESCHERICHIA-COLI; NUCLEOID PROTEINS; EXPRESSION; GENOME; DNA; CHROMOSOME;

D O I：

10.1128/JB.01594-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We performed chromatin immunoprecipitation-microarray analysis to investigate differences in function between StpA and H-NS in Escherichia coli cells. StpA binding regions essentially overlap those of H-NS in wild-type cells, while they are reduced to one-third in the hns mutant. The H-NS binding profile was unaffected by stpA inactivation.

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收藏

页码：2388 / 2391

页数：4

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